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Two of the three conversion steps happen before you swallow. That's why what you brush with sits directly on top of the pathway.
Prebiotic nitrate from mixed berry extract lands on the tongue while you brush, with a vitamin C co-factor. It normally comes from leafy greens, and most people don't eat enough to keep the pathway supplied.
Species at the back of your tongue reduce nitrate to nitrite. Human cells cannot run this reaction, so the bacteria aren't optional. Antibacterial rinses and detergent pastes both reduce that population.
You swallow the nitrite in saliva and your body completes the conversion to nitric oxide, the molecule behind vascular tone and oxygen delivery. A capsule skips the first two stages entirely.
Illustration of the nitrate to nitric oxide pathway. Not to scale.
Everyday acid wear leaves microscopic gaps across the surface. Nano-sized hydroxyapatite is small enough to settle into them and bond.
14%Drag to fill the surface
Illustration of the remineralization mechanism, not a micrograph. Individual results vary.
We make two of these. If the original is the better fit, we'd rather you bought that one.
Fygg Original Prebiotic Toothpaste (3.1% n-HAp) was independently tested in Amaechi et al., J Dent 2025;161:106006. +NO uses the same NanoXIM hydroxyapatite at 2.1% and was not separately tested in that study. The conventional toothpaste column reflects common mass-market formulations, not any single named product.
No proprietary blends and no undisclosed amounts.
Three questions, about fifteen seconds. If the original is right for you, we'll say so.
It can. Think of +NO as an upgrade rather than a swap. It does everything our Original does, at a slightly lower hydroxyapatite level, plus the nitrate pathway. If maximum remineralization is your only priority, Original at 3.1% n-HAp is the stronger choice. If you want your routine doing more than cleaning teeth, this is it.
Because nitric oxide is a gas with a lifespan measured in seconds. You cannot put it in a tube. What you can do is supply the raw material, which is prebiotic nitrate. Your bacteria convert it to nitrite, and your body finishes the job. +NO restores an input that modern oral care tends to strip out.
Yes. +NO contains 2.1% NanoXIM hydroxyapatite, inside the 1–3% range clinical work identifies as optimal for remineralization, sensitivity, and whitening. Original runs 3.1%, so if remineralization is your single priority, start there.
That is the design. Brush twice daily for a steady baseline, then use the mints between meals when you want a larger dose. Test strips let you confirm where you are landing. The three products were built as one routine.
Antibacterial mouthwash works directly against this. It does not distinguish between harmful bacteria and the species performing the nitrate conversion, so it can wipe out the exact population +NO is feeding. If you are using +NO, skip the antiseptic rinse.
[HOLD FOR CLINICAL AND REGULATORY SIGN-OFF. Unlike Fygg Original, which is safe from age 0, the +NO formula contains prebiotic nitrate and needs a defined minimum age. Do not publish until Dr. Burhenne and counsel have set it. Original remains the recommendation for young children.]
Foam comes from SLS, a detergent that strips beneficial bacteria and triggers canker sores in some people. +NO is SLS-free, surfactant-free, and emulsifier-free, which matters twice over here because those ingredients disrupt the bacteria doing the conversion. Give it a few days.
Nano-hydroxyapatite delivers remineralization without the concerns around toxicity, fluorosis, or endocrine disruption. It is biocompatible, so your body recognizes it as its own material. Clinical work shows n-HAp performs comparably to fluoride for cavity prevention and sensitivity.
Roughly 2 to 3 months with twice-daily brushing. The 3-Pack on Subscribe & Save works out cheapest per tube and takes reordering off your list.
30-day satisfaction guarantee. If it is not right for you, reach out and we will make it right.
“Fygg is so much more than a toothpaste. It’s a daily way to support the health and diversity of your oral microbiome, the complex community of microbes that helps maintain balance, not just in the mouth, but throughout the entire body. Fygg supports one of the most accessible and important gateways to lifelong wellness.”
“Fygg is the hydroxyapatite toothpaste I use for myself and my family because of the ingredient quality, not to mention - I also enjoy the taste!”
“I often recommend Fygg to my patients as part of a comprehensive, root-cause approach to health. Its science-backed formulation supports key areas and the beautiful branding is an added bonus.”
“Our practice really loves Fygg toothpaste and varnish! Very few oral hygiene products impress me, after 40 years in practice and these products do. They are truly clinically effective. When selecting nano-Hydroxyapatite products to recommend, sourcing of ingredients MATTERS. Fygg products are one of the few containing “NanoXIM” - it is safe and effective”
“I absolutely love using and recommending Fygg as part of a whole-person plan. The oral microbiome is such a critical place to start in overall health since it's the gateway to the rest of the body. The microbiome impacts all systems of the body, including the immune system and hormone production! I love that I can trust the science-backed, clean ingredients in their oral health products.”
“As a holistic dental hygienist, my focus is always on patient health and oral wellness- it is important to me that products work without toxic ingredients. As a mom, it is equally important that what we use at home sets my kids up for a lifetime of good oral health. I recommend FYGG for my family, friends, and patients! FYGG has helped people with sensitivity and those with cavities. 10 out of 10 would recommend!”
“Fygg has been a miracle for patients with sensitive teeth and gums! Whenever I’ve had patients with temporary crowns that have come off, Fygg works incredibly well as a treatment for sensitivity! We don’t go a day in the office without using it on our patients, and I highly recommend it to all my patients!”
“As a holistic dentist, I’m constantly looking for products that align with my commitment to natural, safe, and effective oral care. Fygg has impressed me with its thoughtful formulation, dedication to quality, and support for overall oral health without the use of harsh chemicals or artificial ingredients. Fygg has set a new standard for what natural toothpaste can achieve.”
“We’ve incorporated Fygg varnish into our remineralization protocol. We avoid products with fluoride because they seal in the white spots. We’ve seen great results for the treatment of white spot lesions by having our patient buy a tube of Fygg varnish and apply it to the inside of their retainers and wear nightly. Beyond impressed by the results!”
